Others have pointed out this card's inherent clunkiness and I'm certainly not going to argue against that. It's definitely a weird card, but it has some some surprising flexibility, too. It's an interrupt, and not specifically a hero or AE interrupt, so it has some extra value with heroes that like to flip a lot and get allies on the table. X-Men and Guardians both have cards that encourage ally swarms/mini-voltrons even in aggression and Gatekeeper can be nice for letting your beefed up allies contribute to thwarting while keeping the table clear of minions. I know some earlier reviews compared this to Chase Them Down but I think there's a better comparison to be made with War Room. War Room has more flexible scheme targets, but Gatekeeper can be triggered by any hero or ally and it removes a much higher threat value (albeit only from the main scheme).
Others mentioned that it potentially has more value in multiplayer and I think this is where the card really shines. It's a great "side board" card. A dedicated thwarter will make this card obsolete, but 5+ years into the game, not every justice player wants to be a dedicated thwarter. A copy of this card in your deck can contribute to keeping threat low with a wider variety of other decks in multiplayer. Hard to recommend building a deck around this card, but it can be a decent flex option.