Supercharged Ironheart

Phase 1: Get Ironheart charged up. Use Maria Hill, Moon Girl, and Kaluu to draw through your deck / find those useful hero cards quickly. Ingenuity ensures you always have available to pay for progress counters. You can also use Rapid Response to re-play Maria Hill and Kaluu for even more card draws so you can reach Fly Over and Photon Beam and use them as much as possible.

Phase 2: At version 3, Ironheart is already hitting hard. Now you can pump her up with R&D Facility, Morale Boost, Moxie, and #Patriot.

In an ideal turn, you would play one of each, although it can be pretty difficult to line all of them up. Fortunately R&D Facility stays in play, and you can use Rapid Response to immediately cycle Patriot back in play (If you're close to pulling this off, I'd save Patriot and avoid using him for blocking / basic actions). Go All Out can really make the best of these boosted stats.

Even better, assuming you're starting from Alter Ego form to use Moxie, you have the potential to use Ready to Rumble, New and Improved, and Falcon to ready yourself 3 times allowing maximum efficiency on your boosted stats. It's not out of the question to play most if not all these cards, once your supports/allies are in play shrinking your deck size, plus utilizing card draws to beef up your hand and afford everything.

Even if you don't max out a turn with the best possible play, you're still going to be hitting hard with boosted stats almost every turn, and the villain will not last long!