This is a card every protection player should be aware of going forward. Outside of Bait and Switch, this is the only Protection card that explicitly removes threat, addressing one of Protection's greatest soft spots. Unlike similar Protection cards in this vein - Unflappable, Electrostatic Armor, and Dauntless - Hard to Ignore lacks the "Max 1 per player" restriction, allowing us to jam 3 in a list and not think twice about it.
Obviously this goes up in value the more you want to be defending and the greater ability you have to prevent damage. Groot fits the bill best due to his growth counters, but Spider-Man and Quicksilver also come to mind as heroes who can defend often.
For a 2 card investment, we expect about 3-4 threat removal (Inconspicuous, Multitasking, Lay Down the Law), and we can definitely get there with Hard to Ignore.
A strong card I think you should play!