I think Domino is an under-rated ally. She can do so many useful things:

• Keeping Hawkeye's quiver full as shown by Man-is-Obsolete (https://marvelcdb.com/decklist/view/32092/lucky-domino-arrow-1.0) - the same trick works with Aunt May & Uncle Ben, or Piotr's Studio;
• Cueing a for Hulk ally so you can actually use him for his attack (https://marvelcdb.com/decklist/view/32961/smash-domino-1.0);
• Cheating at Rock, Paper, Scissors (https://marvelcdb.com/decklist/view/34627/pink-ladies-1.0);
• Maximising Magic Blast (https://marvelcdb.com/decklist/view/32129/magic-blast-goes-brrrrrrr-1.0).

I'm sure there's more ways that she could be used that I haven't spotted yet. She's great!